Born in Squinzano (Italy) in 1970, Tiziano Manca attended the Faculty of Philosophy and the Conservatory in Florence, studying Electronic Music and Composition by Romano Pezzati and Salvatore Sciarrino. He completed his degree in Composition receiving a grant from the Foundation Federico del Vecchio. He undertook further studies in Conducting with Piero Bellugi. In 2001 he was composer-in-residence in Japan (Akiyoshidai International Art Village), in 2001-2002 in Royaumont (Paris) and in 2002-2003 at the Akademie Schloss Solitude (Stuttgart). His works have been interpreted by various prestigious ensembles, among others, Ensemble Recherche, Klangforum Wien, musikFabrik, Neue Vocalsolisten, Ensemble Ascolta, Ensemble Mosaik, Collegium Novum Zurich.
Manca's music has been performed among others in Lucerne (Lucerne Festival), Darmstadt (Ferienkurse), Amsterdam (Gaudeamus Music Week), Anvers (Ars Musica), Berlin (Konzerthaus, Festival Ultraschall), Huddersfield (Huddersfield Contemporary Music), Paris (Abbaye de Royaumont), Zürich (Tage für Neue Musik), Buenos Aires (Teatro San Martín) and Japan (Akiyoshidai International Art Village). In March 2004 the Neue Vocalsolisten premiered his Opera La Gabbia in Theaterhaus Stuttgart and in the Lille Opera.
His work includes both instrumental and vocal music in various formations (solo, voice and instruments, music theatre, choir a cappella).
His docARTES doctoral defense took place on May 20, 2022 at Orpheus Institute.